Publications

Publications

2024
Kumar, N., Sharma, S., & Kaushal, PS., Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosomes hibernation promotion factor RafH (2024), Nat Commun 15(1):638.*
Srinivasan, K., Banerjee, A., & Sengupta, J., Cryo-EM structures reveal the molecular mechanism of HflX-mediated erythromycin resistance in mycobacteria (2024), Structure, 32(9):1443-1453.e4.*
Yadav, S & Vinotkumar, KR., Factors affecting macromolecule orientations in thin films formed in cryo-EM (2024), Acta Cryst. D80, 535-550.
Premageetha, GT; Vinothkumar, KR., Bose, S., Exploring Advances in Single Particle CryoEM with Apoferritin: from Blobs to True Atomic Resolution (2024), Int J Biochem Cell Biol.169, 106536.
Hussain, N., Apotikar, A., Shabareesh, P., Mukherjee, S., Burada, AP., Sikdar,     SK., Vinothkumar, KR., Penmatsa, A. Structural insights into pore dynamics of human Pannexin isoforms (2024), Nat Commun. 15, 2942.*
Mishra, R,K., Sharma, P., Khaja, FT., Uday,  AB.,  Hussain, T., Cryo-EM structure of wheat ribosome reveals unique features of the plant ribosomes (2024), Structure. 32(5):562-574.e3.*
Jha, S., Bose, S., Vinothkumar KR. Modeling Ligands into Maps Derived from Electron Cryomicroscopy. (2024), J Vis Exp. Jul 19;209.
Goyal, P.,  Dhanabalan, KV., Scalise, Maria Francesca., Friemann, Rosmarie., Indiveri, Cesare.,  Dobson, Renwick CJ Vinothkumar, K.R., Subramanian, Ramaswamy. Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter. (2024), eLife13:RP98158

 

2023
Ahmad, M., Jha, B., Tiwari, S., Dwivedi, A., Pal, R., Bose, S., Parish, T., Vinothkumar, KR., Biswal, BK. Crystal and CryoEM structures of Mycobacterium enolase provide insights into 2-phosphoglycerate binding and catalysis (2023), IUcrJ:10: 738-753.
Srinivasachari, S., Tiwari, VR., Kharbanda, T., Sowdhamini, R., Subramanian, R. A dimer between monomers and hexamers-oligomeric variations in glucosamine-6-phosphate deaminsae family (2023), PLoS One 18(1): e0271654.
Bangera M, Dungdung A, Prabhu S, Sirajuddin M. Doublet microtubule inner junction protein FAP20 recruits tubulin to the microtubule lattice. (2023), Structure. Dec 7;31(12):1535-1544.e4  
Gautam, S., Mahapa, A., Yeramala, L., Gandhi, A., Krishnan, S.,   Vinothkumar,   KR., Chatterji, D. Regulatory mechanisms of c-di-AMP synthase from Mycobacterium smegmatis revealed by a structure: Function analysis (2023), Prot. Sci. 32:e4568

 

2022
 Bandyopadhyay, P., Pramanick, I., Biswas, R., Sabarinath, PS., Sreedharan,   S., Singh,S., Rajmani, RS., Laxman, S., Dutta, S., Singh, A. (2022), S-adenosyl methionine responsive cystathionine b-synthase modulates sulfurmetabolism and redox balance in Mycobacterium tuberculosis (2022) , Sci .Adv. 8, eabo0097.*
Arya, CA., Ramanathan, G., Vinothkumar, KR., Subramanian, R.
Dimethylformamidase with a unique iron center (2022), Encyclopedia of Inorganic and Bioinorganic Chemistry
Singh, J., Raina, R., Vinothkumar, K.R., Anand, R. Decoding the Mechanism of  Specific RNA targeting by ribosomal methyltransferases (2022), ACS Chem Biol.,17(4):829-839.
Chen, S., Li, J., Vinothkumar, K.R., Henderson, R. Interaction of human erythrocyte catalase with air–water interface in cryoEM (2022), Microscopy, 71(S1), i51-i59.
Jijumon, AS., Bodakuntla, S., Genova, M., Bangera, M., Sackett, V., Besse, L., Maksut, F., Henriot, V., Magiera, M., Sirajuddin, M., Janke, C. Lysate-based pipeline to characterize microtubule-associated proteins uncovers unique microtubule behaviour (2022),  Nat. Cell Biol.24, 253-267.

 

2021
Nasrallah, C., Cannone, G., Briot, J., Rottier, K., Berizzi, AE., Huang, CY., Quast,RB., Hoh, F., Baneres, JL., Malhaire, F., Berto, L., Dumazer, A., Font-Ingles, J.,Gomes-Santacana, X., Catena, J., Kniazeff, J., Goudet, C., Llebaria, A., Pin, JL., Vinothkumar, K.R., Lebon, G. Agonists and allosteric modulators promote signalling from different metabotropic glutamate receptor 5 conformations (2021), Cell Reports. 36, 109648.
Vinothkumar, K.R., Expanding capabilities and infrastructure for cryo-EM  (2021), Nat. Methods 18, 431-432.  
Akbar, S., Bhakta, S., Sengupta, J. Structural insights into the interplay of protein biogenesis factors with the 70s ribosome (2021), Structure 29, 755-767.*  
Menon, ND., Kumar, MS., Babu, TG., Bose, S., Vijayakumar, G., Baswe, M.,
Chatterjee, M., D’Silva, J., Shetty, K., Haripriyan, J., Kumar, A., Nair, S., Somanath, P., Nair, B., Nizet, V., Kumar, G. A Novel N4-like Bacteriophage Isolated from a wastewater Source in South India with activity against several multidrug-resistant clinical Pseudomonas aeruginosa Isolates (2021),  msphere 6, e01215-20. *
 
Vinothkumar, K.R., Arya, CA., Ramanathan, G., Ramaswamy, S. Comparison of CryoEM and X-ray structures of dimethylformamidase  (2021), Prog Biophy. Mol Bio. 160:66-78.  

 

2020
Arya, CA., Yadav, S., Fine, J., Casanal, A., Chopra, G., Ramanthan, G. Vinothkumar, K.R., Ramaswamy, S. A 2-Tyr-1-Carboxylate Mononuclear                 Iron Center is the Active Site of Dimethylformamidase (2020), Angew.Chem.Int.Ed.Engl. V59(39):16961-16966.  
Kumari, A., Kesarwani, S., Javoor, MG., Vinothkumar, K.R., Sirajuddin, M. Structural insights into actin filament recognition by commonly used cellular  actin markers (2020), Embo J. V10:3058.  
 Burada, AP., Vinnkota, R., Kumar, J. Cryo-EM structure of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture (2020), Nat. Stru. Mol. Biol. 27, 84-91. *  
Burada, AP., Vinnkota, R., Kumar, J. The architecture of GluD2 ionotropic delta glutamate receptor elucidated by cryo-EM (2020), J.Stru.Biol. 107546. *  

 

2019
Sathyanarayanan, N., Cannone, G., Gakhar, L., Katagihallimath, N., Sowdhamini,  R., Ramaswamy, S., Vinothkumar, K.R., Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway (2019), Nat Commun. Sep 11;10(1):4127.  
Kumari, J., Vinnakota, R., Kumar J. Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery (2019), Sci.Rep.  Jul16;9(1):10254. *  

(those marked with asterisks are from external users)